How much is a ticket from Rome to Syracuse?

The cheapest tickets from Rome to Syracuse start from $52. The average price for this route is around $92. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the ride from Rome to Syracuse?

The average trip duration from Rome to Syracuse is 16h 35m, covering a distance of 363 miles (586 km). The quickest vehicle can get you there in 11h 5m and is operated by Trenitalia .

Which companies service the Rome to Syracuse route?

Several major companies operate on this route with 1 trips available per day, including services from FlixBus , Trenitalia .

What is the earliest and latest departure time from Rome to Syracuse?

The earliest trip departs from Rome to Syracuse at 7:26am. And the latest trip departs at 11:55pm.

What are the CO₂ emissions for the trip from Rome to Syracuse?

A trip from Rome to Syracuse generates an estimated 14.6363125 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best company from Rome to Syracuse?

According to Busbud customers, the highest-rated company on this route is Trenitalia , with an average rating of 3.9 out of 5 stars based on 58 reviews.

Which company has the best Wi-Fi from Rome to Syracuse?

Based on reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which company has the most timely service from Rome to Syracuse?

According to Busbud traveler reviews, the most timely company on this route is Trenitalia , with a punctuality rating of 4.6 out of 5 stars.

Which company has the cleanest vehicles from Rome to Syracuse?

According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia , with a cleanliness rating of 4.7 out of 5 stars.

Bus and Train Rome to Syracuse from $50 | Refundable Tickets

Previously seen trips

Next departures for Rome to Syracuse on May 15
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	1:15am	Rome Tiburtina Bus Station	19h 25m	8:40pm	Terminal Interbus	No tags
Bus	1:15am	Rome Tiburtina Bus Station	19h 25m	8:40pm	Terminal Interbus	No tags
Bus	2:35am	Rome Tiburtina Bus Station	18h 5m	8:40pm	Terminal Interbus	No tags
Bus	2:35am	Rome Tiburtina Bus Station	18h 5m	8:40pm	Terminal Interbus	No tags
Bus	8:10pm	Rome Tiburtina Bus Station	13h 25m	9:35am	Terminal Interbus	No tags

Compare 2 ways to go from Rome to Syracuse

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 11 hours 11 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

1train per day

11h 11mAverage Duration

365 milesDistance

14kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$52 - $158	Average Duration22h	CO₂ emissions 15kg CO₂e
Train	Average Price$58 - $139	Average Duration11h 11m	CO₂ emissions 14kg CO₂e

Where are the popular stops in Rome and Syracuse?

Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
Visit page
B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
Visit page
D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
Visit page
E
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
Visit page
F
Cesano di Roma
Cesano Di Roma, 00123 Roma RM, Italy
Visit page

Stops in Syracuse

A
S. Teresa Longarini
Via Elorina, 129, 96100 Siracusa SR, Italy
B
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy
Visit page
C
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy
D
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy

Compare companies

FlixBus

3.5/512,643 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Trenitalia

3.9/558 reviews

Staff4.6

Timeliness4.6

Cleanliness4.7

Wifi2.5

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn ICE, ALSA, RegioJet, Rede Expressos, FlixTrain, Trenitalia, Deutsche Bahn, Sindbad, NS Nederlandse Spoorwegen, MarinoBus, Italo

Frequently asked questions about traveling from Rome to Syracuse by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Rome to Syracuse?
The cheapest tickets from Rome to Syracuse start from $52. The average price for this route is around $92. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Rome to Syracuse?
The average trip duration from Rome to Syracuse is 16h 35m, covering a distance of 363 miles (586 km). The quickest vehicle can get you there in 11h 5m and is operated by Trenitalia.
Which companies service the Rome to Syracuse route?
Several major companies operate on this route with 1 trips available per day, including services from FlixBus, Trenitalia.
What is the earliest and latest departure time from Rome to Syracuse?
The earliest trip departs from Rome to Syracuse at 7:26am. And the latest trip departs at 11:55pm.
What are the CO₂ emissions for the trip from Rome to Syracuse?
A trip from Rome to Syracuse generates an estimated 14.6363125 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Rome to Syracuse?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 58 reviews.
Which company has the best Wi-Fi from Rome to Syracuse?
Based on reviews on Busbud, the company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which company has the most timely service from Rome to Syracuse?
According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Rome to Syracuse?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/13

$71

05/14

$57

Today

$59

05/16

$54

05/17

$57

05/18

$50

05/19

$59

05/20

$59

The cheapest trip from Rome to Syracuse was searched and found on May 18, 2026 with a price of $50

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Rome to Syracuse, as early as possible.

You can expect to pay from $50 to $134 for a bus or train ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $50 which is on 2026-05-18.