What is the travel distance from Florence to Wilmington?

The distance separating Florence and Wilmington is 443 miles (714 km).

What are the departure and arrival stations when taking the bus from Florence to Wilmington?

The majority of buses traveling from Florence to Wilmington start their journey at Florence Bus Station and wind up at Wilmington Bus Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

Bus Florence to Wilmington from $54 | Refundable Tickets

TomorrowAug 30

SunAug 31

MonSep 1

from $115

TueSep 2

from $80

WedSep 3

ThuSep 4

FriSep 5

SatSep 6

Cheap buses leaving Monday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: September 1 at 4:15pm
Departure city: Florence
Departure location: Bus station
Arrival time: September 2 at 5:55am
Destination city: Wilmington
Destination location: Wilmington Bus Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 13h 40m
This trip is recommended because it is: Fastest
Departure time: September 1 at 12:05am
Departure city: Florence
Departure location: Florence, SC
Arrival time: September 1 at 12:20pm
Destination city: Wilmington
Destination location: Newark (DE)
Operated by: FlixBus
Vehicle: BusDuration: 12h 15m
Departure time: September 1 at 4:15pm
Departure city: Florence
Departure location: Bus station
Arrival time: September 2 at 1:30pm
Destination city: Wilmington
Destination location: Delaware Rest Stop S
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 21h 15m
Departure time: September 1 at 12:05am
Departure city: Florence
Departure location: Florence, SC
Arrival time: September 1 at 12:20pm
Destination city: Wilmington
Destination location: Newark (DE)
Operated by: FlixBus
Vehicle: BusDuration: 12h 15m
Departure time: September 1 at 12:05am
Departure city: Florence
Departure location: Florence, SC
Arrival time: September 1 at 1:40pm
Destination city: Wilmington
Destination location: Wilmington Bus Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 13h 35m

Accepted payments

Compare 2 ways to go from Florence to Wilmington.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$64 - $244	Average Duration13h 40m	CO₂ emissions 18kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$91 - $255	Average Duration9h 51m	CO₂ emissions 66kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Florence to Wilmington

Among the sustainable travel choices, the train stands out as the good way to reach Wilmington. The journey takes about 9 hours 51 minutes and with fares starting at just $91, it presents an excellent value for a comfortable ride.

2train per day

9h 51mAverage Duration

$91Cheapest ticket

66kgCO₂ emissions

Bus Florence, SC, US to Wilmington, DE: Trip Overview

Average ticket price$97

Average bus trip duration13h 40m

Number of daily buses5

Earliest bus departure12:05am

Distance448 miles (722 km)

Latest bus departure4:15pm

Compare bus companies

FlixBus

3.5/510,305 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,216 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Florence to Wilmington Bus

Busbud helps you find a bus from Florence to Wilmington. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Wilmington.

Discover how much the bus trip from Florence to Wilmington will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Florence and Wilmington?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Wilmington

A - Wilmington Bus Station

B - Wilmington Station

C - Wilmington Bus Stop

Frequently asked questions for your trip Florence, SC, US - Wilmington, DE

What is the travel distance from Florence to Wilmington?
What are the departure and arrival stations when taking the bus from Florence to Wilmington?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/27

$67

08/28

$59

Today

$98

08/30

$54

08/31

No data

09/01

$191

09/02

$83

09/03

$58

The cheapest trip from Florence, SC, US to Wilmington, DE was searched and found on Aug 30, 2025 with a price of $54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Wilmington, DE, as early as possible.

You can expect to pay from $54 to $204 for a bus ticket from Florence, SC, US to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at $54 which is on 2025-08-30.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Wilmington!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Wilmington.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Florence to Wilmington will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Wilmington while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Florence, SC, US to Wilmington, DE?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time13h 40m	Avg Price$97	Daily Departures5
Vehicle TypeTrain	Travel Time9h 51m	Avg Price$141	Daily Departures2

Will you be returning to Florence, SC, US by bus?

Bus from Wilmington, DE to Florence, SC, US

You can also go to Wilmington, DE by train

Train from Florence, SC, US to Wilmington, DE

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Florence, SC, US to Wilmington, DE

Cheap buses leaving Monday

One passenger / one way

One passenger / one way

Compare 2 ways to go from Florence to Wilmington.

Bus Florence, SC, US to Wilmington, DE: Trip Overview

Compare bus companies

Florence to Wilmington Bus

Where are the popular stops in Florence and Wilmington?

Frequently asked questions for your trip Florence, SC, US - Wilmington, DE

What is the travel distance from Florence to Wilmington?

What are the departure and arrival stations when taking the bus from Florence to Wilmington?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Florence, SC, US to Wilmington, DE?

Will you be returning to Florence, SC, US by bus?

You can also go to Wilmington, DE by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular Buses Connecting Wilmington

Buses Leaving from Wilmington

Buses Going to Wilmington

Popular routes in this country

Popular airport transfers