Find coaches from Florence, SC, US to Wilmington, DE

Next departures

Next departures from Florence to Wilmington on 1 September
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus station
Wilmington Bus StationCheapest
FlixBus
Florence, SC
Newark (DE)Fastest
FlixBus + Greyhound Lines, Inc.
Bus station
Delaware Rest Stop SNo tags
FlixBus
Florence, SC
Newark (DE)No tags
FlixBus + Greyhound Lines, Inc.
Florence, SC
Wilmington Bus StationNo tags

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Compare 2 ways to travel from Florence to Wilmington

Bus
Average priceUS$64 - US$244Average duration13h 40m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$91 - US$255Average duration9h 51m
66kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Florence to Wilmington

Among the sustainable travel choices, the train stands out as a good way to reach Wilmington. The journey takes about 9 hours 51 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

2train per day
9h 51mAverage duration
US$91Cheapest ticket
66kgCO₂ emissions

Bus Florence, SC, US to Wilmington, DE: Trip Overview

Average ticket priceUS$97
Average bus trip duration13h 40m
Number of daily buses5
Earliest bus departure00:05
Distance448 miles
Latest bus departure16:15

Florence to Wilmington Bus

Busbud helps you find a bus from Florence to Wilmington. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Wilmington.

Discover how much the bus trip from Florence to Wilmington will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Florence, SC, US - Wilmington, DE

  1. How far is Wilmington from Florence by coach?

    The distance between Florence and Wilmington by coach is approximately 443 miles (714 km).

  2. Is there a way to reach Wilmington from Florence without flying?

    You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/08
US$67
28/08
US$59
Today
US$98
30/08
US$54
31/08
No data
01/09
US$191
02/09
US$83
03/09
US$58
busbud logoThe cheapest trip from Florence, SC, US to Wilmington, DE was searched and found on 30 Aug 2025 with a price of US$54

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Wilmington, DE as early as possible.

You can expect to pay from US$54 to US$204 for a bus ticket from Florence, SC, US to Wilmington, DE based on the last 2 days. You can expect to find the cheapest price for the trip at US$54, which is on 2025-08-30.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Florence and Wilmington!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Wilmington.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Florence to Wilmington will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Wilmington while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Florence, SC, US to Wilmington, DE?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Wilmington, DE to Florence, SC, US

You can also go to Wilmington, DE by train

Train from Florence, SC, US to Wilmington, DE

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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