Find coaches from Boston, MA, US to Winston-Salem

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Today29 Aug
from US$121
Tomorrow30 Aug
Sun31 Aug
Mon1 Sept
Tue2 Sept
Wed3 Sept
Thu4 Sept
Fri5 Sept

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 29 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 30 August at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 29 August at
    Departure city: Boston
    Departure location: Brookline
    Arrival time: 30 August at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 30 August at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: 31 August at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 29 August at
    Departure city: Boston
    Departure location: Brookline
    Arrival time: 30 August at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Boston to Winston-Salem

Bus
Average priceUS$75 - US$179Average duration21h 30m
26kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$131 - US$192Average duration1d 1h
94kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Boston to Winston-Salem

Among the sustainable travel choices, the bus stands out as a good way to reach Winston-Salem. The journey takes about 21 hours 30 minutes and with fares starting at just US$75, it presents an excellent value for a comfortable ride.

6bus per day
21h 30mAverage duration
US$75Cheapest ticket
26kgCO₂ emissions

Bus Boston, MA, US to Winston-Salem: Trip Overview

Average ticket priceUS$121
Average bus trip duration21h 30m
Number of daily buses6
Earliest bus departure01:30
Distance650 miles
Latest bus departure22:00

Boston to Winston-Salem Bus

Busbud helps you find a bus from Boston to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Boston to Winston-Salem from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from Boston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Boston, MA, US - Winston-Salem

  1. How far is Winston-Salem from Boston by coach?

    The journey from Boston to Winston-Salem by coach covers an approximate distance of 654 miles (1054 km).

  2. What is the best way to go from Boston to Winston-Salem without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
27/08
US$67
28/08
No data
Today
US$107
30/08
No data
31/08
No data
01/09
No data
02/09
No data
03/09
No data
busbud logoThe cheapest trip from Boston, MA, US to Winston-Salem was searched and found on 27 Aug 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Winston-Salem as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Boston to Winston-Salem, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Winston-Salem.

Make a music playlist for your bus ride from Boston to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Boston, MA, US to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Boston, MA, US by bus?

Bus from Winston-Salem to Boston, MA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

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