Bus Tickets from Santa Ana, US to Boston, MA, US

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Previously seen trips

One passenger / one way

  • Departure time: August 6 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 10 at
    Destination city: Boston
    Destination location: Brookline
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 10 at
    Destination city: Boston
    Destination location: 151 Steel Pl, Cambridge
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 10 at
    Destination city: Boston
    Destination location: Boston (South Station)
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Santa Ana
    Departure location: Santa Ana Bus Station
    Arrival time: August 10 at
    Destination city: Boston
    Destination location: 151 Steel Pl, Cambridge
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Santa Ana
    Departure location: Anaheim Regional Transportation Intermodal Center
    Arrival time: August 10 at
    Destination city: Boston
    Destination location: 151 Steel Pl, Cambridge
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

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Bus Santa Ana, US to Boston, MA, US: Trip Overview

Average Ticket PriceUS$280
Average Bus Trip Duration3d 7h
Number of daily buses15
Earliest bus departure7:10am
Distance4145 km
Latest bus departure9:40pm

Santa Ana to Boston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to Boston.

Bus service from Santa Ana to Boston will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana, US - Boston, MA, US

  1. How far is Santa Ana from Boston?

    Santa Ana and Boston are 4159 km (2579 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Santa Ana to Boston?

    Buses departing from Santa Ana Greyhound Bus Station in Santa Ana will take you to Back Bay Station in Boston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-27
No data
08-28
US$257
Today
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08-30
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08-31
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09-01
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09-03
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busbud logoThe cheapest trip from Santa Ana, US to Boston, MA, US was searched and found on Aug 28, 2025 with a price of US$257

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to Boston, MA, US, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to Boston but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santa Ana to Boston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to Boston that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Ana to Boston.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Ana, US by bus?

Bus from Boston, MA, US to Santa Ana, US

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