Trains tickets from Greenville, SC to Indianapolis

Next departures

Next departures for Greenville to Indianapolis on September 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
Greenville Station
Greyhound Amtrak StationCheapestFastest
Amtrak
Greenville Station
Greyhound Amtrak StationNo tags

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Compare 2 ways to go from Greenville to Indianapolis.

Bus
Average Price$71 - $155Average Duration19h 10m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$139 - $258Average Duration1d 2h
58kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Indianapolis

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 19 hours 10 minutes and with fares starting at just $71, it presents an excellent value for a comfortable ride.

8bus per day
19h 10mAverage Duration
$71Cheapest ticket
16kgCO₂ emissions

Train Greenville, SC to Indianapolis: Trip Overview

Please note, this information is subject to change.

Average ticket price$176
Average train trip duration1d 2h
Number of daily trains1
Earliest train departure2:23am
Distance396 miles (638 km)

Greenville to Indianapolis Train

Busbud helps you find a train from Greenville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make it our job to connect you with the most dependable companies that offer train service from Greenville to Indianapolis.

Discover how much the train trip from Greenville to Indianapolis will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Greenville, SC - Indianapolis

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/30
No data
08/31
$168
Today
No data
09/02
No data
09/03
$248
09/04
No data
09/05
$168
09/06
No data
busbud logoThe cheapest trip from Greenville, SC to Indianapolis was searched and found on Aug 31, 2025 with a price of $168

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Indianapolis, as early as possible.

You can expect to pay from $168 to $843 for a train ticket from Greenville, SC to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2025-09-05.

About Train Travel

Train Travel Tips

There are many train stations in the world, check it station pages on Busbud to get all information you need.

Whether you take a regional or high-speed train to Indianapolis, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

With up to 30x less CO2 emissions for your train journey between Greenville and Indianapolis, the train is an ecological alternative to flights or personal cars.

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Greenville to Indianapolis.

Did you know?

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

Will you be returning to Greenville, SC by train?

Train from Indianapolis to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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