Busbud recommends taking the bus from Wilmington to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours and with fares starting at just $83, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With Busbud, comparing and booking tickets for a bus from Wilmington to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Wilmington to Chicago from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Chicago from Wilmington, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Wilmington and Chicago?
Stops in Wilmington
A - Wilmington Bus Station
Wilmington Bus Station, 101 N French St, Wilmington, DE 19801, USAWilmington Bus Station
Frequently asked questions for your trip Wilmington, DE - Chicago
How far is Wilmington from Chicago?
The distance between the two cities is 649 miles (1046 km).
What are the departure and arrival stations when taking the bus from Wilmington to Chicago?
Most of the buses traveling from Wilmington to Chicago leave from Wilmington Bus Station and arrive at Downtown Greyhound Station. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Lake Michigan, Robie House, Brookfield Zoo, Lincoln Park Conservatory and Museum of Science and Industry.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/21
$88
08/22
$114
Today
$86
08/24
$91
08/25
$88
08/26
$90
08/27
$86
08/28
$100
The cheapest trip from Wilmington, DE to Chicago was searched and found on Aug 23, 2025 with a price of $86
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Chicago, as early as possible.
You can expect to pay from $86 to $211 for a bus ticket from Wilmington, DE to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-08-27.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Wilmington to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Wilmington to Chicago, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to Chicago.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Chicago.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
What's the cheapest way to go from Wilmington, DE to Chicago?
The bus is the cheapest travel choice for this destination
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
Busbud recommends taking the bus from Wilmington to Chicago
The cheapest trip from Wilmington, DE to Chicago was searched and found on Aug 23, 2025 with a price of $86
The bus is the cheapest travel choice for this destination
