Bus Tickets from Salisbury, MD, US to Chicago

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TodayAug 29
from $149
TomorrowAug 30
from $128
SunAug 31
MonSep 1
TueSep 2
WedSep 3
ThuSep 4
FriSep 5

Next departures to Chicago

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 30 at
    Departure city: Salisbury
    Departure location: Salisbury (Park & Ride)
    Arrival time: August 31 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 30 at
    Departure city: Salisbury
    Departure location: BayRunner Shuttle
    Arrival time: August 31 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 30 at
    Departure city: Salisbury
    Departure location: BayRunner Shuttle
    Arrival time: August 31 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 30 at
    Departure city: Salisbury
    Departure location: Salisbury (Park & Ride)
    Arrival time: August 31 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 30 at
    Departure city: Salisbury
    Departure location: BayRunner Shuttle
    Arrival time: August 31 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Bus Salisbury, MD, US to Chicago: Trip Overview

Average ticket price$166
Average bus trip duration1d 5h
Number of daily buses8
Earliest bus departure1:00am
Distance678 miles (1092 km)
Latest bus departure5:30pm

Salisbury to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Salisbury to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Salisbury to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Salisbury to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Salisbury, MD, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
No data
08/28
No data
Today
No data
08/30
$237
08/31
No data
09/01
No data
09/02
No data
09/03
No data
busbud logoThe cheapest trip from Salisbury, MD, US to Chicago was searched and found on Aug 30, 2025 with a price of $237

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, MD, US to Chicago, as early as possible.

You can expect to pay from $237 to $704 for a bus ticket from Salisbury, MD, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $237 which is on 2025-08-30.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Salisbury to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Salisbury to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Salisbury to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Salisbury to Chicago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Salisbury, MD, US by bus?

Bus from Chicago to Salisbury, MD, US

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