What is the distance between Rome and Lyon?

Rome and Lyon are 464 miles (748 km) apart.

What are the departure and arrival stations when taking the bus from Rome to Lyon?

If you're headed to Lyon from Rome, chances are that your bus will depart from Rome Ciampino Airport and arrive at Lyon Airport. These are the primary departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Lyon?

Once in Lyon, you can start exploring the city and discover its surroundings. The top sights and things to do are Musée des Beaux Arts, Musée d’Art Contemporain, Opéra de Lyon, Institut Lumière and Musée des Tissus.

Rome to Lyon from $42 | Refundable Tickets

FriAug 22

from $145

TodayAug 23

from $105

TomorrowAug 24

from $113

MonAug 25

from $91

TueAug 26

from $71

WedAug 27

from $73

ThuAug 28

from $71

FriAug 29

from $54

Cheap buses leaving today

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: August 23 at 7:45am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: August 23 at 10:40pm
Destination city: Lyon
Destination location: Perrache
Operated by: Flixbus
Vehicle: BusDuration: 14h 55m
This trip is recommended because it is: Fastest
Departure time: August 23 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: August 23 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m
Departure time: August 23 at 3:20pm
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: August 24 at 6:10am
Destination city: Lyon
Destination location: Lyon - Perrache Bus Station
Operated by: BlaBlaCar Bus
Vehicle: BusDuration: 14h 50m
Departure time: August 23 at 12:10am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: August 23 at 4:15pm
Destination city: Lyon
Destination location: Perrache
Operated by: Flixbus
Vehicle: BusDuration: 16h 5m
Departure time: August 23 at 7:00am
Departure city: Rome
Departure location: Rome Tiburtina Bus Station
Arrival time: August 23 at 9:30pm
Destination city: Lyon
Destination location: Lyon Lyon Perrache Bus Station
Operated by: Itabus
Vehicle: BusDuration: 14h 30m

Accepted payments

Compare 3 ways to go from Rome to Lyon.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$47 - $323	Average Duration16h 55m	CO₂ emissions 19kg CO₂e5 out of 5 stars	Cheapest
Train	Average Price$177 - $540	Average Duration8h 12m	CO₂ emissions 18kg CO₂e5 out of 5 stars	FastestMost eco-friendly
Carpool	Average Price$66 - $97	Average Duration10h 40m	CO₂ emissions 31kg CO₂e4 out of 5 stars

Busbud recommends carpooling from Rome to Lyon

Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 10 hours 40 minutes and with fares starting at just $66, it presents an excellent value for a comfortable ride.

1carpool per day

10h 40mAverage Duration

$66Cheapest ticket

31kgCO₂ emissions

Bus Rome to Lyon: Trip Overview

Average ticket price$106

Average bus trip duration16h 55m

Number of daily buses21

Earliest bus departure12:10am

Distance465 miles (750 km)

Latest bus departure11:50pm

Compare bus companies

FlixBus

3.5/510,186 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Itabus

4/5916 reviews

Staff4.3

Timeliness3.1

Cleanliness4.2

Wifi3.2

BlaBlaCar Bus

3.5/510,745 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

RegioJet

4/51,048 reviews

Staff4.4

Timeliness4

Cleanliness4.4

Wifi3.8

FlixBus

3.5/510,186 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

FR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Rede Expressos, Trenitalia, Sindbad, Infobus

Rome to Lyon Bus

Busbud helps you find a bus from Rome to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Rome to Lyon from the most reliable bus companies operating this trip.

Discover how much the bus trip from Rome to Lyon will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in Rome and Lyon?

Stops in Rome

A - Rome Ciampino Airport

B - Rome Fiumicino Airport

C - Rome Tiburtina Bus Station

D - Castro Pretorio

E - Roma

F - Anagnina

Stops in Lyon

A - Lyon Airport

B - Perrache

C - Les Charrières

D - Lyon

E - Quai de Saoune

F - Villeurbanne INSA

Frequently asked questions for your trip Rome - Lyon

What is the distance between Rome and Lyon?
What are the departure and arrival stations when taking the bus from Rome to Lyon?
What are the best sights and things to do in Lyon?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/21

$102

08/22

$98

Today

$98

08/24

$102

08/25

$86

08/26

$64

08/27

$67

08/28

$64

The cheapest trip from Rome to Lyon was searched and found on Aug 28, 2025 with a price of $64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon, as early as possible.

You can expect to pay from $64 to $214 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-08-28.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Rome and Lyon!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Lyon, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rome to Lyon will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Rome to Lyon.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Rome by bus?

Bus from Lyon to Rome

You can also go to Lyon by train

Train from Rome to Lyon

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Rome to Lyon

One passenger / one way

Cheap buses leaving today

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 3 ways to go from Rome to Lyon.

Bus Rome to Lyon: Trip Overview

Compare bus companies

Rome to Lyon Bus

Where are the popular stops in Rome and Lyon?

Frequently asked questions for your trip Rome - Lyon

What is the distance between Rome and Lyon?

What are the departure and arrival stations when taking the bus from Rome to Lyon?

What are the best sights and things to do in Lyon?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Rome by bus?

You can also go to Lyon by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Rome

Buses Leaving from Rome

Buses Going to Rome

Popular Buses Connecting Lyon

Buses Leaving from Lyon

Buses Going to Lyon

Popular routes in this country

Popular airport transfers