Bus and Train from Pisa to Rome: Tickets & Schedules

Next available departures

Next departures for Pisa to Rome on May 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
MarinoBus
Fermata dell'autobus Pisa
Rome Tiburtina Bus StationCheapest
Trenitalia FRECCIARGENTO
Piazza della Stazione, 10
TiburtinaFastest
Trenitalia FRECCIABIANCA
Piazza della Stazione, 10
TerminiNo tags
Flixbus
Parcheggio Via Pietransantina
Rome Tiburtina Bus StationNo tags
Trenitalia FRECCIABIANCA
Piazza della Stazione, 10
TerminiNo tags

Last refresh of the prices: Today at 9:25 PM CEST.

Compare 2 ways to go from Pisa to Rome

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 3 hours 47 minutes and with fares starting at just $23, it presents an excellent value for a comfortable ride.

10train per day
3h 47mAverage Duration
165 milesDistance
6kgCO₂ emissions
Average Price$18 - $163Average Duration5h 50m
7kg CO₂e
Average Price$23 - $204Average Duration3h 47m
6kg CO₂e

Frequently asked questions about traveling from Pisa to Rome by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is a ticket from Pisa to Rome?

    The cheapest tickets from Pisa to Rome start from $18. The average price for this route is around $32. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the ride from Pisa to Rome?

    The average trip duration from Pisa to Rome is 4h 48m, covering a distance of 166 miles (267 km). The quickest vehicle can get you there in 2h 9m and is operated by Trenitalia.

  3. Which companies service the Pisa to Rome route?

    Several major companies operate on this route with 11 trips available per day, including services from FlixBus, BusItalia, MarinoBus, Itabus, Trenitalia.

  4. What is the earliest and latest departure time from Pisa to Rome?

    The earliest trip departs from Pisa to Rome at 12:25am. And the latest trip departs at 11:30pm.

  5. What are the CO₂ emissions for the trip from Pisa to Rome?

    A trip from Pisa to Rome generates an estimated 6.6655875 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best company from Pisa to Rome?

    According to Busbud customers, the highest-rated company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 920 reviews.

  7. Which company has the best Wi-Fi from Pisa to Rome?

    Based on reviews on Busbud, the company BusItalia has the best Wi-Fi rating with a score of 3.8.

  8. Which company has the most timely service from Pisa to Rome?

    According to Busbud traveler reviews, the most timely company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.

  9. Which company has the cleanest vehicles from Pisa to Rome?

    According to Busbud traveler reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/10
$26
05/11
$23
Today
$32
05/13
$21
05/14
$16
05/15
$15
05/16
$15
05/17
$15
busbud logoThe cheapest trip from Pisa to Rome was searched and found on May 15, 2026 with a price of $15

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Rome, as early as possible.

You can expect to pay from $15 to $159 for a bus or train ticket from Pisa to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $15 which is on 2026-05-15.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Pisa to Rome?

busbud logoThe Bus is the cheapest travel choice for this destination

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