Busbud recommends taking the bus from Harrisburg to Chicago
Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 18 hours 25 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With Busbud, comparing and booking tickets for a bus from Harrisburg to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Harrisburg to Chicago from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Harrisburg to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Harrisburg and Chicago?
Frequently asked questions for your trip Harrisburg - Chicago
What is the travel distance from Harrisburg to Chicago?
Harrisburg and Chicago are 571 miles (920 km) apart.
What are the departure and arrival stations when taking the bus from Harrisburg to Chicago?
The majority of buses traveling from Harrisburg to Chicago start their journey at Harrisburg Bieber Greyhound Station and wind up at Downtown Greyhound Station. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Lake Michigan, Lincoln Park Conservatory, Shedd Aquarium, Lincoln Park Zoo and Museum of Science and Industry.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/24
$84
08/25
$110
Today
$75
08/27
$86
08/28
$64
08/29
$104
08/30
$89
08/31
$92
The cheapest trip from Harrisburg to Chicago was searched and found on Aug 28, 2025 with a price of $64
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Chicago, as early as possible.
You can expect to pay from $64 to $204 for a bus ticket from Harrisburg to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-08-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Harrisburg to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Harrisburg to Chicago, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Harrisburg to Chicago that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Harrisburg to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Harrisburg to Chicago?
The bus is the cheapest travel choice for this destination
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
Busbud recommends taking the bus from Harrisburg to Chicago
The cheapest trip from Harrisburg to Chicago was searched and found on Aug 28, 2025 with a price of $64
The bus is the cheapest travel choice for this destination
