Bus Tickets from Greenville, SC to Winston-Salem

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TodayAug 29
TomorrowAug 30
SunAug 31
from $36
MonSep 1
TueSep 2
WedSep 3
ThuSep 4
FriSep 5

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 31 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: August 31 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 31 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: August 31 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: August 31 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: August 31 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: September 2 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Expreso + Tornado Bus
    Expreso + Tornado Bus
    Vehicle: BusDuration:

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Compare 2 ways to go from Greenville to Winston-Salem.

Bus
Average Price$32 - $153Average Duration3h 10m
6kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$59 - $59Average Duration7h 42m
22kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the train from Greenville to Winston-Salem

Among the sustainable travel choices, the train stands out as the good way to reach Winston-Salem. The journey takes about 7 hours 42 minutes and with fares starting at just $59, it presents an excellent value for a comfortable ride.

2train per day
7h 42mAverage Duration
$59Cheapest ticket
22kgCO₂ emissions

Bus Greenville, SC to Winston-Salem: Trip Overview

Average ticket price$143
Average bus trip duration3h 10m
Number of daily buses3
Earliest bus departure10:50am
Distance146 miles (234 km)
Latest bus departure3:02pm

Greenville to Winston-Salem Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Winston-Salem is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Greenville to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Greenville, SC - Winston-Salem

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
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08/28
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Today
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08/30
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08/31
$29
09/01
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09/02
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09/03
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busbud logoThe cheapest trip from Greenville, SC to Winston-Salem was searched and found on Aug 31, 2025 with a price of $29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Winston-Salem, as early as possible.

You can expect to pay from $29 to $145 for a bus ticket from Greenville, SC to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $29 which is on 2025-08-31.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Greenville to Winston-Salem.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Winston-Salem will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville, SC by bus?

Bus from Winston-Salem to Greenville, SC

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