Bus Tickets from Gainesville, FL to Indianapolis

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WedAug 20
ThuAug 21
FriAug 22
from $102
SatAug 23
SunAug 24
from $108
MonAug 25
TueAug 26
WedAug 27

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 22 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: August 23 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 22 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: August 22 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: August 23 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: August 23 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: August 22 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: August 22 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Gainesville, FL to Indianapolis: Trip Overview

Average ticket price$162
Average bus trip duration1d
Number of daily buses12
Earliest bus departure1:10am
Distance726 miles (1170 km)
Latest bus departure10:40pm

Gainesville to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Gainesville to Indianapolis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Gainesville to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Gainesville, FL - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/16
No data
08/17
$116
Today
$127
08/19
$142
08/20
No data
08/21
No data
08/22
$94
08/23
No data
busbud logoThe cheapest trip from Gainesville, FL to Indianapolis was searched and found on Aug 22, 2025 with a price of $94

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Indianapolis, as early as possible.

You can expect to pay from $94 to $246 for a bus ticket from Gainesville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $94 which is on 2025-08-22.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Gainesville to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Gainesville to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Gainesville to Indianapolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Gainesville, FL by bus?

Bus from Indianapolis to Gainesville, FL

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