What is the distance between Florence and Tampa?

Florence and Tampa are 464 miles (747 km) apart.

What are the departure and arrival stations when taking the bus from Florence to Tampa?

If you're headed to Tampa from Florence, chances are that your bus will depart from Florence Bus Station and arrive at Tampa 13th Avenue Bus Stop (McDonald's). These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Florence to Tampa from $64 | Refundable Tickets

SatAug 30

SunAug 31

from $80

MonSep 1

from $100

TueSep 2

from $74

WedSep 3

from $71

ThuSep 4

FriSep 5

SatSep 6

Cheap buses leaving Sunday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: August 31 at 12:55pm
Departure city: Florence
Departure location: Bus station
Arrival time: September 1 at 6:00am
Destination city: Tampa
Destination location: Tampa Bus Station
Operated by: FlixBus
Vehicle: BusDuration: 17h 5m
This trip is recommended because it is: Fastest
Departure time: August 31 at 5:45am
Departure city: Florence
Departure location: Florence, SC
Arrival time: August 31 at 10:25pm
Destination city: Tampa
Destination location: Tampa Bus Station
Operated by: FlixBus
Vehicle: BusDuration: 16h 40m
Departure time: August 31 at 4:15pm
Departure city: Florence
Departure location: Bus station
Arrival time: September 1 at 6:10pm
Destination city: Tampa
Destination location: Tampa Bus Station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 1d 1h
Departure time: August 31 at 5:45am
Departure city: Florence
Departure location: Florence, SC
Arrival time: August 31 at 10:25pm
Destination city: Tampa
Destination location: Tampa Bus Station
Operated by: FlixBus
Vehicle: BusDuration: 16h 40m
Departure time: August 31 at 12:55pm
Departure city: Florence
Departure location: Bus station
Arrival time: September 1 at 12:30pm
Destination city: Tampa
Destination location: University of South Florida
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 23h 35m

Accepted payments

Compare 2 ways to go from Florence to Tampa.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$66 - $222	Average Duration23h 35m	CO₂ emissions 18kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$73 - $136	Average Duration18h 30m	CO₂ emissions 67kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Florence to Tampa

Among the sustainable travel choices, the train stands out as the good way to reach Tampa. The journey takes about 18 hours 30 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.

1train per day

18h 30mAverage Duration

$73Cheapest ticket

67kgCO₂ emissions

Bus Florence, SC, US to Tampa: Trip Overview

Average ticket price$88

Average bus trip duration23h 35m

Number of daily buses5

Earliest bus departure5:45am

Distance451 miles (727 km)

Latest bus departure4:15pm

Compare bus companies

FlixBus

3.5/510,288 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,212 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Florence to Tampa Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Tampa.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Tampa.

Whether it is cheap bus tickets or more luxurious buses going to Tampa from Florence, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Florence and Tampa?

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Stops in Tampa

A - Tampa 13th Avenue Bus Stop (McDonald's)

B - Tampa USF, FL

C - Greyhound Station

D - E Sligh Ave

E - N Marion St & E Laurel St

F - Port of Tampa

Frequently asked questions for your trip Florence, SC, US - Tampa

What is the distance between Florence and Tampa?
What are the departure and arrival stations when taking the bus from Florence to Tampa?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/26

$78

08/27

No data

Today

No data

08/29

$101

08/30

No data

08/31

$73

09/01

$95

09/02

$67

The cheapest trip from Florence, SC, US to Tampa was searched and found on Sep 2, 2025 with a price of $67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa, as early as possible.

You can expect to pay from $67 to $110 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-09-02.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Tampa but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Tampa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Tampa.

Make a music playlist for your bus ride from Florence to Tampa, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence, SC, US to Tampa?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time23h 35m	Avg Price$88	Daily Departures5
Vehicle TypeTrain	Travel Time18h 30m	Avg Price$126	Daily Departures1

Will you be returning to Florence, SC, US by bus?

Bus from Tampa to Florence, SC, US

You can also go to Tampa by train

Train from Florence, SC, US to Tampa

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Florence, SC, US to Tampa

Cheap buses leaving Sunday

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Florence to Tampa.

Bus Florence, SC, US to Tampa: Trip Overview

Compare bus companies

Florence to Tampa Bus

Where are the popular stops in Florence and Tampa?

Frequently asked questions for your trip Florence, SC, US - Tampa

What is the distance between Florence and Tampa?

What are the departure and arrival stations when taking the bus from Florence to Tampa?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Florence, SC, US to Tampa?

Will you be returning to Florence, SC, US by bus?

You can also go to Tampa by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence

Popular Buses Connecting Tampa

Buses Leaving from Tampa

Buses Going to Tampa

Popular routes in this country

Popular airport transfers