Compare 2 ways to go from Florence to Durham.
Busbud recommends taking the bus from Florence to DurhamAmong the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 3 hours 30 minutes and with fares starting at just $36, it presents an excellent value for a comfortable ride.
Bus Florence, SC, US to Durham, NC, US: Trip Overview
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Florence to Durham Bus
With Busbud, comparing and booking tickets for a bus from Florence to Durham is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Durham.
Whether it is cheap bus tickets or more luxurious buses going to Durham from Florence, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Florence and Durham?
Frequently asked questions for your trip Florence, SC, US - Durham, NC, US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Durham, NC, US was searched and found on Aug 29, 2025 with a price of $33To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Durham, NC, US, as early as possible.
You can expect to pay from $33 to $60 for a bus ticket from Florence, SC, US to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-08-31.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Florence to Durham.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Florence to Durham.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Durham.
Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Durham while indulging in miles on end of beautiful scenic views.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Florence, SC, US to Durham, NC, US?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Florence
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Popular Buses Connecting Durham
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Buses Going to Durham
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