Bus Tickets from Des Moines to Milwaukee

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TodaySep 2
TomorrowSep 3
from $73
ThuSep 4
from $56
FriSep 5
from $62
SatSep 6
from $62
SunSep 7
MonSep 8
from $67
TueSep 9

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 3 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: September 3 at
    Destination city: Milwaukee
    Destination location: Milwaukee Bus Station, St. Paul & N6th road.
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 3 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: September 3 at
    Destination city: Milwaukee
    Destination location: Milwaukee Mitchell MKE Airport
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: September 3 at
    Destination city: Milwaukee
    Destination location: Milwaukee Mitchell MKE Airport
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Des Moines
    Departure location: Des Moines
    Arrival time: September 4 at
    Destination city: Milwaukee
    Destination location: St. Paul & N5th
    Operated by: Jefferson LinesJefferson Lines
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Des Moines
    Departure location: Des Moines
    Arrival time: September 4 at
    Destination city: Milwaukee
    Destination location: St. Paul & N5th
    Operated by: Jefferson Lines + Land to Air Express
    Jefferson Lines + Land to Air Express
    Vehicle: BusDuration:

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Bus Des Moines to Milwaukee: Trip Overview

Average ticket price$69
Average bus trip duration11h 35m
Number of daily buses3
Earliest bus departure4:20am
Distance306 miles (493 km)
Latest bus departure11:30pm

Des Moines to Milwaukee Bus

Busbud helps you find a bus from Des Moines to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Milwaukee from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Des Moines - Milwaukee

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/31
No data
09/01
No data
Today
No data
09/03
$168
09/04
No data
09/05
No data
09/06
No data
09/07
No data
busbud logoThe cheapest trip from Des Moines to Milwaukee was searched and found on Sep 3, 2025 with a price of $168

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Milwaukee, as early as possible.

You can expect to pay from $168 to $168 for a bus ticket from Des Moines to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at $168 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Milwaukee!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Milwaukee, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Milwaukee.

Make a music playlist for your bus ride from Des Moines to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from Milwaukee to Des Moines

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