Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Midway Truck Plaza Bus Stop | Columbus (E Mound St) | Cheapest | ||||
| Bus | Midway Truck Plaza Bus Stop | Columbus (E Mound St) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Midway Truck Plaza Bus Stop | 100 E Rich St | No tags | ||||
| Bus | Columbia Wabash Station | Columbus (E Mound St) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Columbia Wabash Station | 100 E Rich St | No tags |
Last refresh of the prices: Last Tuesday at 11:00 PM CDT.
Get from Columbia to Columbus
The journey takes about 16 hours 50 minutes and with fares starting at just $110, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbia and Columbus?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Columbia, MO to Columbus, OH by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbia to Columbus?
The cheapest bus tickets from Columbia to Columbus start from $110. The average price for this route is around $131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbia to Columbus?
The average bus trip duration from Columbia to Columbus is 16h 50m, covering a distance of 505 miles (813 km). The quickest bus can get you there in 12h 55m and is operated by Greyhound.
Which bus companies service the Columbia to Columbus route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from Columbia to Columbus?
The earliest bus departs from Columbia to Columbus at 8:30am. And the latest bus departs at 8:35pm.
What are the CO₂ emissions for the bus trip from Columbia to Columbus?
A bus trip from Columbia to Columbus generates an estimated 20.32285 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to Columbus, OH was searched and found on May 18, 2026 with a price of $90To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to Columbus, OH, as early as possible.
You can expect to pay from $90 to $116 for a bus ticket from Columbia, MO to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2026-05-18.
