Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Bus Palermo | Rome Tiburtina Bus Station | Cheapest | |||||
 | Palermo Centrale | Termini | Fastest | |||||
| Terminal Bus Palermo | Rome Tiburtina Bus Station | No tags | |||||
 | Terminal Bus Palermo | Tiburtina | No tags | |||||
| Palermo Centrale | Termini | No tags | |||||
 | Terminal Bus Palermo | Aeroporto Ciampino Airport (CIA) | No tags | |||||
| Terminal Bus Palermo | Rome Tiburtina Bus Station | No tags | |||||
| Terminal Bus Palermo | Rome Fiumicino Airport | No tags |
Last refresh of the prices: Today at 10:52 AM CEST.
Compare 2 ways to travel from Palermo to Rome
Among the sustainable travel choices, the Bus stands out as a good way to reach Rome. The journey takes about 17 hours 55 minutes and with fares starting at just US$23, it presents an excellent value for a comfortable ride.
Bus stations and stops in Palermo and Rome
Stops in Palermo
- A
Palermo Centrale
Stazione Centrale - Cupani 3, 90123, 90123 Palermo PA, Italy - B
Vespri
Via del Vespro, 90127 Palermo PA, Italy - C
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy - D
Francia
90146 Palermo PA, Italy - E
Guadagna
90124 Palermo PA, Italy - F
La Malfa
90146 Palermo PA, Italy
Stops in Rome
- A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy - B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy - D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy - F
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
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Frequently asked questions about travelling from Palermo to Rome by bus or train
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is a ticket from Palermo to Rome?
The cheapest tickets from Palermo to Rome start at US$23. The average price for this route is around US$106. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the journey from Palermo to Rome?
The average trip duration from Palermo to Rome is 14h 44m, covering a distance of 427 km. The quickest vehicle can get you there in 11h 29m and is operated by Trenitalia.
Which companies operate the Palermo to Rome route?
Several major companies operate on this route with 5 trips available per day, including services from FlixBus, Itabus, Autoservizi Salemi, Trenitalia.
What are the earliest and latest departure times from Palermo to Rome?
The earliest trip from Palermo to Rome departs at 07:00. The latest trip departs at 21:10.
What are the CO₂ emissions for the journey from Palermo to Rome?
A trip from Palermo to Rome generates an estimated 10.6501375 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Which is the best company from Palermo to Rome?
According to Busbud customers, the highest-rated company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 554 reviews.
Which company has the best Wi-Fi from Palermo to Rome?
Based on reviews on Busbud, the company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.
Which company has the most punctual service from Palermo to Rome?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.4 out of 5 stars.
Which company has the cleanest vehicles from Palermo to Rome?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Rome was searched and found on 07 Sept 2026 with a price of US$30To save money and make sure you get the best seat, it's a good idea to buy your bus and train tickets from Palermo to Rome, as early as possible.
You can expect to pay between US$30 and US$270 for a bus or train ticket from Palermo to Rome based on the past 2 days. You can expect to find the lowest price for the trip at US$30 which is on 2026-09-07.
Usually FlixBus, Autoservizi Salemi, Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Palermo to Rome?
The Bus is the cheapest travel choice for this destination
