Find coaches from Wytheville to Chicago

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Previously seen journeys

One passenger / one way

  • Departure time: 1 December at
    Departure city: Wytheville
    Departure location: Wytheville Bus Station
    Arrival time: 1 December at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 1 December at
    Departure city: Wytheville
    Departure location: Wytheville Bus Station
    Arrival time: 1 December at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 1 December at
    Departure city: Wytheville
    Departure location: Wytheville Bus Station
    Arrival time: 2 December at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: 1 December at
    Departure city: Wytheville
    Departure location: Wytheville Bus Station
    Arrival time: 2 December at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: 1 December at
    Departure city: Wytheville
    Departure location: Wytheville Bus Station
    Arrival time: 2 December at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Wytheville to Chicago: Trip Overview

Average ticket priceUS$199
Average bus trip duration18h 45m
Number of daily buses5
Earliest bus departure02:50
Distance495 miles
Latest bus departure14:30

Wytheville to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Wytheville to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Wytheville to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Wytheville to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Wytheville - Chicago

  1. How far is Chicago from Wytheville by coach?

    The distance between Wytheville and Chicago by coach is approximately 487 miles (785 km).

  2. What is the best way to go from Wytheville to Chicago without flying?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/08
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27/08
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Today
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29/08
US$139
30/08
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31/08
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01/09
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02/09
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busbud logoThe cheapest trip from Wytheville to Chicago was searched and found on 29 Aug 2025 with a price of US$139

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wytheville to Chicago as early as possible.

You can expect to pay from US$139 to US$167 for a bus ticket from Wytheville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$139, which is on 2025-08-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Wytheville to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Wytheville to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wytheville to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wytheville to Chicago.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Wytheville by bus?

Bus from Chicago to Wytheville

Why choose Busbud?

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