Find coaches from Charleston, WV, US to St. Louis

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Today30 Aug
from US$155
Tomorrow31 Aug
from US$106
Mon1 Sept
Tue2 Sept
Wed3 Sept
Thu4 Sept
Fri5 Sept
Sat6 Sept

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 31 August at
    Departure city: Charleston
    Departure location: Charleston Bus Station
    Arrival time: 31 August at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Charleston to St. Louis

Bus
Average priceUS$72 - US$138Average duration15h 15m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$159 - US$1,225Average duration23h 38m
68kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Charleston to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 15 hours 15 minutes and with fares starting at just US$72, it presents an excellent value for a comfortable ride.

1bus per day
15h 15mAverage duration
US$72Cheapest ticket
19kgCO₂ emissions

Bus Charleston, WV, US to St. Louis: Trip Overview

Average ticket priceUS$106
Average bus trip duration15h 15m
Number of daily buses1
Earliest bus departure09:20
Distance463 miles

Charleston to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Charleston to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Charleston to St. Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Charleston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Charleston, WV, US - St. Louis

  1. How far is St. Louis from Charleston by coach?

    The distance between Charleston and St. Louis by coach is approximately 464 miles (747 km).

  2. Is there a way to reach St. Louis from Charleston without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/08
No data
29/08
US$118
Today
US$147
31/08
US$98
01/09
No data
02/09
No data
03/09
No data
04/09
No data
busbud logoThe cheapest trip from Charleston, WV, US to St. Louis was searched and found on 31 Aug 2025 with a price of US$98

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to St. Louis as early as possible.

You can expect to pay from US$98 to US$147 for a bus ticket from Charleston, WV, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$98, which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charleston to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Charleston to St. Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Charleston, WV, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston, WV, US by bus?

Bus from St. Louis to Charleston, WV, US

You can also go to St. Louis by train

Train from Charleston, WV, US to St. Louis

Why choose Busbud?

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