Next available departures

Next departures for Rome to Palermo on September 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	Cheapest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	Fastest
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	6:55pm	Aeroporto Ciampino Airport (CIA)	20h 20m	3:15pm	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on September 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	Cheapest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	Fastest
Wi‑Fi Toilet Power outlets	3:45pm	Rome Tiburtina Bus Station	19h 15m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	6:55pm	Aeroporto Ciampino Airport (CIA)	20h 20m	3:15pm	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on September 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	Cheapest
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	Fastest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	3:45pm	Rome Tiburtina Bus Station	19h 15m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on September 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	Cheapest
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	Fastest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	No tags
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on September 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	Cheapest
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	Fastest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on September 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	Cheapest
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	Fastest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:26am	Termini	11h 38m	7:04pm	Palermo Centrale	No tags
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	No tags

Next departures for Rome to Palermo on October 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	1:20am	Rome Tiburtina Bus Station	13h 55m	3:15pm	Terminal Bus Palermo	Cheapest
	8:00pm	Tiburtina	11h 45m	7:45am	Terminal Bus Palermo	Fastest
Wi‑Fi Toilet Power outlets	9:00pm	Rome Tiburtina Bus Station	14h	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	11:30pm	Rome Tiburtina Bus Station	15h 45m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	7:55pm	Rome Fiumicino Airport	15h 5m	11:00am	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	10:35pm	Rome Fiumicino Airport	16h 40m	3:15pm	Terminal Bus Palermo	No tags
Wi‑Fi Toilet Power outlets	6:55pm	Aeroporto Ciampino Airport (CIA)	20h 20m	3:15pm	Terminal Bus Palermo	No tags

Last refresh of the prices: Yesterday at 11:06 PM CEST.

Compare 2 ways to go from Rome to Palermo

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Palermo. The journey takes about 15 hours 5 minutes, and with fares starting at just CLP 22,848, it presents an excellent value for a comfortable ride.

7bus per day

15h 5mAverage Duration

426 kmDistance

11kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCLP 22,848 - CLP 137,037	Average Duration15h 5m	CO₂ emissions 11kg CO₂e
Train	Average PriceCLP 39,754 - CLP 141,711	Average Duration11h 38m	CO₂ emissions 10kg CO₂e

Bus stations and stops in Rome and Palermo

Stops in Rome

A
Termini
Piazza dei Cinquecento 1, 00185 Roma RM, Italy
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B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
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C
Rome Fiumicino Airport (FCO), Train station
Fiumicino Aeroporto, 00054 Fiumicino RM, Italy
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D
Roma S. Pietro
Roma S.Pietro, 00165 Roma RM, Italy
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E
Rome Ciampino Airport
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F
Roma Trastevere
Roma Trastevere Railway Station, 00152 Roma RM, Italy
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Stops in Palermo

A
Palermo Centrale
Stazione Centrale - Cupani 3, 90123, 90123 Palermo PA, Italy
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B
Vespri
Via del Vespro, 90127 Palermo PA, Italy
Visit page
C
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy
Visit page
D
Francia
90146 Palermo PA, Italy
E
Guadagna
90124 Palermo PA, Italy
F
La Malfa
90146 Palermo PA, Italy

Compare companies

FlixBus

3.5/515,875 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Trenitalia

3.9/571 reviews

Staff4.5

Timeliness4.5

Cleanliness4.8

Wi‑Fi2.9

Itabus

3.8/51,080 reviews

Staff4.3

Timeliness3.1

Cleanliness4.1

Wi‑Fi2.8

Autoservizi Salemi

4.3/5564 reviews

Staff4.8

Timeliness4.3

Cleanliness4.7

Wi‑Fi3.9

According to 19 reviews, Autoservizi Salemi received a 4.7-star rating for this journey. Travellers were especially satisfied with the staff and the timeliness, but some complained about the Wi‑Fi. Autoservizi Salemi ticket prices on this trip start at CLP 39,486

Autoservizi Salemi Rome Palermo recent customer reviews

Ottima esperienza personale molto gentile ed aperto alle esigenze dei passeggeri

Ettore B.

May 13, 2023

Very nice

Osagie Richard E.

August 26, 2025

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, NS Nederlandse Spoorwegen, Deutsche Bahn, Deutsche Bahn Regio, Sindbad, Italo

Frequently asked questions about travelling from Rome to Palermo by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Rome to Palermo?
The cheapest tickets from Rome to Palermo start at CLP 22,848. The average price for this route is around CLP 79,319. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Rome to Palermo?
The average trip duration from Rome to Palermo is 13h 21m, covering a distance of 427 km. The quickest vehicle can get you there in 11h 32m and is operated by Trenitalia.
Which companies service the Rome to Palermo route?
Several major companies operate on this route with 4 trips available per day, including services from FlixBus, Itabus, Autoservizi Salemi, Trenitalia.
What is the earliest and latest departure time from Rome to Palermo?
The earliest trip from Rome to Palermo departs at 1:20am. And the latest trip departs at 11:45pm.
What are the CO₂ emissions for the trip from Rome to Palermo?
A trip from Rome to Palermo generates an estimated 10.6639375 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Rome to Palermo?
According to Busbud customers, the highest-rated company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 563 reviews.
Which company has the best Wi-Fi from Rome to Palermo?
Based on Busbud reviews, the company Autoservizi Salemi has the highest Wi‑Fi rating with a score of 3.9.
Which company has the most on-time service from Rome to Palermo?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.5 out of 5 stars.
Which company has the cleanest vehicles from Rome to Palermo?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.8 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09-23

CLP 54,916

09-24

CLP 64,612

Today

CLP 54,272

09-26

CLP 47,310

09-27

CLP 45,003

09-28

CLP 39,229

09-29

CLP 35,188

09-30

CLP 39,229

The cheapest trip from Rome to Palermo was searched and found on Sep 29, 2026 with a price of CLP 35,188

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Rome to Palermo, as early as possible.

You can expect to pay between CLP 35,188 and CLP 133,818 for a bus or train ticket from Rome to Palermo based on the past 2 days. You can expect to find the lowest price for this trip at CLP 35,188 on 2026-09-29.

Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.