Bus Tickets from Syracuse, US to Indianapolis

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TodayAug 31
TomorrowSep 1
TueSep 2
WedSep 3
ThuSep 4
from US$85
FriSep 5
from US$86
SatSep 6
SunSep 7

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 4 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 6 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 4 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Syracuse to Indianapolis

Average PriceUS$72 - US$204Average Duration23h
23kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$120 - US$250Average Duration1d 1h
83kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Syracuse to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours, and with fares starting at just US$72, it presents an excellent value for a comfortable ride.

6bus per day
23hAverage Duration
US$72Cheapest ticket
23kgCO₂ emissions

Bus Syracuse, US to Indianapolis: Trip Overview

Average Ticket PriceUS$106
Average Bus Trip Duration23h
Number of daily buses6
Earliest bus departure12:20am
Distance910 km
Latest bus departure9:00pm

Syracuse to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Syracuse to Indianapolis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Syracuse to Indianapolis.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Syracuse, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Syracuse, US - Indianapolis

  1. What is the travel distance from Syracuse to Indianapolis?

    It's about 912 km (565 miles) from Syracuse to Indianapolis.

  2. What are the departure and arrival locations for buses traveling from Syracuse to Indianapolis?

    Buses departing from Syracuse Airport in Syracuse will take you to Greyhound Amtrak Station in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-29
US$266
08-30
US$109
Today
No data
09-01
US$135
09-02
US$114
09-03
No data
09-04
US$85
09-05
US$93
busbud logoThe cheapest trip from Syracuse, US to Indianapolis was searched and found on Sep 4, 2025 with a price of US$85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Indianapolis, as early as possible.

You can expect to pay from US$85 to US$266 for a bus ticket from Syracuse, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$85 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Syracuse to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Syracuse to Indianapolis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Syracuse to Indianapolis.

Make a music playlist for your bus ride from Syracuse to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Syracuse, US to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse, US by bus?

Bus from Indianapolis to Syracuse, US

You can also go to Indianapolis by train

Train from Syracuse, US to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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