Bus Tickets from St. Louis to Madison, WI

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TodaySep 2
TomorrowSep 3
ThuSep 4
from US$66
FriSep 5
from US$72
SatSep 6
from US$71
SunSep 7
from US$71
MonSep 8
from US$69
TueSep 9

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 4 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 5 at
    Destination city: Madison
    Destination location: North Lake St
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 4 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 5 at
    Destination city: Madison
    Destination location: Dutch Mill Park & Ride
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 4 at
    Destination city: Madison
    Destination location: North Lake St
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 4 at
    Destination city: Madison
    Destination location: Dutch Mill Park & Ride
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: St. Louis
    Departure location: Gateway Station
    Arrival time: September 5 at
    Destination city: Madison
    Destination location: Dutch Mill Park & Ride
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from St. Louis to Madison

Bus
Average PriceUS$60 - US$153Average Duration13h 35m
12kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$74 - US$623Average Duration10h 50m
45kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from St. Louis to Madison

Among the sustainable travel choices, the train stands out as a good way to reach Madison. The journey takes about 10 hours 50 minutes, and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

9train per day
10h 50mAverage Duration
US$74Cheapest ticket
45kgCO₂ emissions

Bus St. Louis to Madison, WI: Trip Overview

Average Ticket PriceUS$71
Average Bus Trip Duration13h 35m
Number of daily buses3
Earliest bus departure2:00am
Distance498 km
Latest bus departure11:30pm

St. Louis to Madison Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Madison is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from St. Louis to Madison from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from St. Louis to Madison, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St. Louis - Madison, WI

  1. What is the travel distance from St. Louis to Madison?

    St. Louis and Madison are 500 km (310 miles) apart.

  2. What are the departure and arrival locations for buses traveling from St. Louis to Madison?

    Buses departing from Gateway Station in St. Louis will take you to UW Memorial Union in Madison.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$68
09-01
US$64
Today
No data
09-03
No data
09-04
US$59
09-05
US$65
09-06
US$64
09-07
US$64
busbud logoThe cheapest trip from St. Louis to Madison, WI was searched and found on Sep 4, 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Madison, WI, as early as possible.

You can expect to pay from US$59 to US$68 for a bus ticket from St. Louis to Madison, WI based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to Madison.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Madison, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Madison that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from St. Louis to Madison while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from St. Louis to Madison, WI?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Madison, WI to St. Louis

Why choose Busbud?

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