Bus Tickets from Santa Fe, AR to San Luis, AR

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TodayAug 24
TomorrowAug 25
TueAug 26
WedAug 27
ThuAug 28
from US$45
FriAug 29
SatAug 30
SunAug 31

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 28 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: August 28 at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: La 20 de JunioLa 20 de Junio
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 28 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: August 29 at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: AndesmarAndesmar
    Vehicle: BusDuration:
  • Departure time: August 28 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: August 28 at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: La 20 de JunioLa 20 de Junio
    Vehicle: BusDuration:
  • Departure time: August 28 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: August 28 at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: Flecha BusFlecha Bus
    Vehicle: BusDuration:
  • Departure time: August 28 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: August 29 at
    Destination city: San Luis
    Destination location: Estación de Interconexión Regional de Ómnibus de San Luis
    Operated by: AndesmarAndesmar
    Vehicle: BusDuration:

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Bus Santa Fe, AR to San Luis, AR: Trip Overview

Average Ticket PriceUS$55
Average Bus Trip Duration11h 30m
Number of daily buses3
Earliest bus departure2:00am
Distance556 km
Latest bus departure9:00pm

Santa Fe to San Luis Bus

Busbud helps you find a bus from Santa Fe to San Luis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santa Fe to San Luis.

Whether it is cheap bus tickets or more luxurious buses going to San Luis from Santa Fe, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santa Fe, AR - San Luis, AR

  1. What is the distance between Santa Fe and San Luis?

    The distance between Santa Fe and San Luis is approximately 561 km (348 miles).

  2. What are the departure and arrival locations for buses traveling from Santa Fe to San Luis?

    Buses departing from Estación Terminal de Ómnibius, Santa Fe in Santa Fe will take you to Estación de Interconexión Regional de Ómnibus de San Luis in San Luis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-22
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08-23
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Today
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08-25
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08-26
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08-27
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08-28
US$41
08-29
No data
busbud logoThe cheapest trip from Santa Fe, AR to San Luis, AR was searched and found on Aug 28, 2025 with a price of US$41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to San Luis, AR, as early as possible.

You can expect to pay from US$41 to US$62 for a bus ticket from Santa Fe, AR to San Luis, AR based on the last 2 days. You can expect to find the cheapest price for the trip at US$41 which is on 2025-08-28.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santa Fe and San Luis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santa Fe to San Luis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santa Fe to San Luis.

Tune out to the fine sounds of your best music playlist on your bus trip from Santa Fe to San Luis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Santa Fe, AR by bus?

Bus from San Luis, AR to Santa Fe, AR

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