Bus Tickets from New Orleans to Greenville, SC

Find affordable bus tickets from New Orleans to Greenville, SC with flexible options. Book your trip now

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TodayAug 29
TomorrowAug 30
from US$94
SunAug 31
from US$98
MonSep 1
from US$143
TueSep 2
WedSep 3
ThuSep 4
FriSep 5
from US$97

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 30 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: August 31 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 30 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: August 31 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 30 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: August 31 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from New Orleans to Greenville

Average PriceUS$73 - US$209Average Duration17h 5m
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$134 - US$572Average Duration16h 3m
82kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from New Orleans to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 17 hours 5 minutes, and with fares starting at just US$73, it presents an excellent value for a comfortable ride.

2bus per day
17h 5mAverage Duration
US$73Cheapest ticket
23kgCO₂ emissions

Bus New Orleans to Greenville, SC: Trip Overview

Average Ticket PriceUS$98
Average Bus Trip Duration17h 5m
Number of daily buses2
Earliest bus departure1:00pm
Distance909 km
Latest bus departure11:35pm

New Orleans to Greenville Bus

With Busbud, comparing and booking tickets for a bus from New Orleans to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from New Orleans to Greenville from the most reliable bus companies operating this trip.

Discover how much the bus trip from New Orleans to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip New Orleans - Greenville, SC

  1. What is the distance between New Orleans and Greenville?

    New Orleans and Greenville are 905 km (561 miles) apart.

  2. What are the departure and arrival locations for buses traveling from New Orleans to Greenville?

    Buses departing from Union Passenger Terminal in New Orleans will take you to Guadalajara Supermarket Bus Stop in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-27
US$89
08-28
US$95
Today
US$107
08-30
US$87
08-31
US$91
09-01
US$135
09-02
No data
09-03
No data
busbud logoThe cheapest trip from New Orleans to Greenville, SC was searched and found on Aug 30, 2025 with a price of US$87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Greenville, SC, as early as possible.

You can expect to pay from US$87 to US$139 for a bus ticket from New Orleans to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$87 which is on 2025-08-30.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from New Orleans to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Greenville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from New Orleans to Greenville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from New Orleans to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from New Orleans to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to New Orleans by bus?

Bus from Greenville, SC to New Orleans

You can also go to Greenville, SC by train

Train from New Orleans to Greenville, SC

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