Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Milan (Assago M2) | Terminal Bus Palermo | Cheapest | ||||
 | Bus | Milan San Donato Bus Station | Terminal Bus Palermo | Fastest | ||||
| Bus | Lampugnano | Terminal Bus Palermo | No tags | ||||
| Bus | Lampugnano bus station | Terminal Bus Palermo | No tags | ||||
| Bus | Lampugnano bus station | Terminal Bus Palermo | No tags |
Last refresh of the prices: Yesterday at 11:53 PM CEST.
Get from Milano to Palermo
The journey takes about 1 day, 1 hour 55 minutes, and with fares starting at just $78, it presents an excellent value for a comfortable ride.
Where are the popular stops in Milano and Palermo?
Stops in Milano
- BPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giuseppe Impastato, 27, 20138 Milano, Italy
- DVia Giulio Natta, 228, 20151 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
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Frequently asked questions about travelling from Milano to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Palermo?
The cheapest bus tickets from Milano to Palermo start from $78. The average price for this route is around $149. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Palermo?
The average bus travel time from Milano to Palermo is 1d 1h, covering a distance of 897 km. The quickest bus can get you there in 21h and is operated by Autoservizi Salemi.
Which bus companies service the Milano to Palermo route?
Several major bus companies operate on this route with 18 buses available per day, including services from FlixBus, Autoservizi Salemi.
What are the earliest and latest departure times for the bus from Milano to Palermo?
The earliest bus departs from Milano to Palermo at 3:05am. And the latest bus departs at 11:05pm.
What are the CO₂ emissions for the bus trip from Milano to Palermo?
A bus trip from Milano to Palermo generates an estimated 22.400125 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milano to Palermo?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 496 reviews.
Which bus company has the best Wi-Fi from Milano to Palermo?
Based on Busbud reviews, the bus company Autoservizi Salemi has the highest Wi-Fi rating with a score of 4.0.
Which bus company has the best on-time performance from Milano to Palermo?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.2 out of 5 stars.
Which bus company has the cleanest buses from Milano to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Palermo was searched and found on May 18, 2026 with a price of $85To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.
You can expect to pay from $85 to $295 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $85 which is on 2026-05-18.
