Bus Tickets from Lyon to Palermo

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TodayAug 21
TomorrowAug 22
SatAug 23
SunAug 24
MonAug 25
from US$115
TueAug 26
WedAug 27
ThuAug 28

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 25 at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: August 27 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 25 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: August 26 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: August 25 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: August 26 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: August 25 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: August 26 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: August 25 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: August 27 at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

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Bus Lyon to Palermo: Trip Overview

Average Ticket PriceUS$259
Average Bus Trip Duration1d 11h
Number of daily buses3
Earliest bus departure1:15am
Distance1088 km
Latest bus departure11:30pm

Lyon to Palermo Bus

With Busbud, comparing and booking tickets for a bus from Lyon to Palermo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Lyon to Palermo from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Lyon to Palermo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Lyon - Palermo

  1. How far is Lyon from Palermo?

    It's about 1103 km (684 miles) from Lyon to Palermo.

  2. What are the departure and arrival locations for buses traveling from Lyon to Palermo?

    Buses departing from Lyon Airport in Lyon will take you to Terminal Bus Palermo in Palermo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-19
No data
08-20
No data
Today
No data
08-22
US$150
08-23
No data
08-24
No data
08-25
US$112
08-26
No data
busbud logoThe cheapest trip from Lyon to Palermo was searched and found on Aug 25, 2025 with a price of US$112

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Palermo, as early as possible.

You can expect to pay from US$112 to US$170 for a bus ticket from Lyon to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$112 which is on 2025-08-25.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Lyon to Palermo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Palermo, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Lyon to Palermo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Lyon to Palermo while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Palermo to Lyon

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