Bus Tickets from Durham, NC, US to Greenville, SC

Next departures

Next departures for Durham to Greenville on September 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Durham Greyhound Bus Station
1116 Woodruff RdCheapest
Tornado Bus
Durham
Greenville, (SC - Taqueria Guadalajara #3)Fastest
Wanda Coach
BP Gas Station
1111 Woodruff RoadNo tags
Greyhound Lines, Inc.
Durham Greyhound Bus Station
1116 Woodruff RdNo tags
FlixBus
Durham Greyhound Bus Station
1116 Woodruff RdNo tags

Accepted payments

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  • China Union Pay
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  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Durham to Greenville

Bus
Average PriceUS$40 - US$153Average Duration4h 45m
8kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$52 - US$127Average Duration10h 23m
31kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 4 hours 45 minutes, and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

8bus per day
4h 45mAverage Duration
US$40Cheapest ticket
8kgCO₂ emissions

Bus Durham, NC, US to Greenville, SC: Trip Overview

Average Ticket PriceUS$52
Average Bus Trip Duration4h 45m
Number of daily buses8
Earliest bus departure1:30am
Distance334 km
Latest bus departure2:50pm

Durham to Greenville Bus

Busbud helps you find a bus from Durham to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Durham, NC, US - Greenville, SC

  1. How far is Durham from Greenville?

    The distance between Durham and Greenville is around 342 km (212 miles).

  2. What are the departure and arrival locations for buses traveling from Durham to Greenville?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-30
US$37
08-31
US$39
Today
US$39
09-02
US$39
09-03
US$36
09-04
US$34
09-05
US$37
09-06
US$35
busbud logoThe cheapest trip from Durham, NC, US to Greenville, SC was searched and found on Sep 4, 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Greenville, SC, as early as possible.

You can expect to pay from US$34 to US$145 for a bus ticket from Durham, NC, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$34 which is on 2025-09-04.

Usually Tornado Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Greenville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Greenville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Greenville.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Durham, NC, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Greenville, SC to Durham, NC, US

You can also go to Greenville, SC by train

Train from Durham, NC, US to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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